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A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.
Entry Term(s)
Chromogranin
Granin
Granins
Secretogranin
Secretogranins
Registry Numbers
0
Previous Indexing
Chromaffin System (1966-1972)
Nerve Tissue Proteins (1966-1972)
Public MeSH Note
1991; see NERVE TISSUE PROTEINS 1973-1990; SECRETOGRANINS was indexed under CHROMOGRANINS 1985-2006
A group of acidic proteins that are major components of SECRETORY GRANULES in the endocrine and neuroendocrine cells. They play important roles in the aggregation, packaging, sorting, and processing of secretory protein prior to secretion. They are cleaved to release biologically active peptides. There are various types of granins, usually classified by their sources.