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A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.
Entry Term(s)
Antigens, CD178
CD178 Antigen
CD178 Antigens
CD95 Antigen Ligand
CD95 Ligand
CD95L
Fas Ligand
Fas Ligand (FasL)
FasL Protein
TNF Superfamily, Member 6
Tumor Necrosis Factor Ligand Superfamily Member 6
Registry Numbers
0
Public MeSH Note
2007; FAS LIGAND PROTEIN was indexed under TUMOR NECROSIS FACTORS and MEMBRANE GLYCOPROTEINS 1994-2006
A transmembrane protein belonging to the tumor necrosis factor superfamily that was originally discovered on cells of the lymphoid-myeloid lineage, including activated T-LYMPHOCYTES and NATURAL KILLER CELLS. It plays an important role in immune homeostasis and cell-mediated toxicity by binding to the FAS RECEPTOR and triggering APOPTOSIS.