MeSH Browser

MeSH Heading: Fibrinolysin
Tree Number(s): D08.811.277.656.300.760.330; D08.811.277.656.959.350.330
Unique ID: D005341
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D005341
Scope Note: A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.
Entry Term(s): Fibrogammin; Glu-Plasmin; Plasmin; Protease F; Thrombolysin
Pharm Action: Fibrinolytic Agents
Registry Number: EC 3.4.21.7
Public MeSH Note: 2010, 1963-1992; see PLASMIN 1993-2009; for PLASMIN see FIBRINOLYSIN 1963-92
History Note: 2010, 1963-1992;
Date Established: 2010/01/01
Date of Entry: 1999/01/01
Revision Date: 2016/07/05

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Endopeptidases [D08.811.277.656.300]
        
        Serine Endopeptidases [D08.811.277.656.300.760]
        
        Acrosin [D08.811.277.656.300.760.030]
        
        Cathepsin G [D08.811.277.656.300.760.066]
        
        Chymases [D08.811.277.656.300.760.103]
        
        Chymotrypsin [D08.811.277.656.300.760.176]
        
        Complement Factor B [D08.811.277.656.300.760.198]
        
        Complement Factor D [D08.811.277.656.300.760.200]
        
        Complement Factor I [D08.811.277.656.300.760.210]
        
        Endopeptidase K [D08.811.277.656.300.760.247]
        
        Enteropeptidase [D08.811.277.656.300.760.284]
        
        Factor VIIa [D08.811.277.656.300.760.300]
        
        Factor IXa [D08.811.277.656.300.760.310]
        
        Factor Xa [D08.811.277.656.300.760.315]
        
        Factor XIa [D08.811.277.656.300.760.320]
        
        Factor XIIa [D08.811.277.656.300.760.324]
        
        Fibrinolysin [D08.811.277.656.300.760.330]
        
        Furin [D08.811.277.656.300.760.353]
        
        Granzymes [D08.811.277.656.300.760.397]
        
        High-Temperature Requirement A Serine Peptidase 1 [D08.811.277.656.300.760.420]
        
        High-Temperature Requirement A Serine Peptidase 2 [D08.811.277.656.300.760.431]
        
        Kallikreins [D08.811.277.656.300.760.442]
        
        Lactoferrin [D08.811.277.656.300.760.471]
        
        Mannose-Binding Protein-Associated Serine Proteases [D08.811.277.656.300.760.501]
        
        Myeloblastin [D08.811.277.656.300.760.530]
        
        Pancreatic Elastase [D08.811.277.656.300.760.560]
        
        Plasminogen Activators [D08.811.277.656.300.760.635]
        
        Prolyl Oligopeptidases [D08.811.277.656.300.760.637]
        
        Pronase [D08.811.277.656.300.760.638]
        
        Proprotein Convertase 1 [D08.811.277.656.300.760.640]
        
        Proprotein Convertase 2 [D08.811.277.656.300.760.646]
        
        Proprotein Convertase 5 [D08.811.277.656.300.760.648]
        
        Proprotein Convertase 9 [D08.811.277.656.300.760.718]
        
        Reelin Protein [D08.811.277.656.300.760.753]
        
        Subtilisins [D08.811.277.656.300.760.787]
        
        Thrombin [D08.811.277.656.300.760.855]
        
        Tissue Plasminogen Activator [D08.811.277.656.300.760.875]
        
        Trypsin [D08.811.277.656.300.760.895]
        
        Tryptases [D08.811.277.656.300.760.902]
        
        Urokinase-Type Plasminogen Activator [D08.811.277.656.300.760.910]
        
        Venombin A [D08.811.277.656.300.760.955]

Enzymes and Coenzymes [D08]
- Enzymes [D08.811]
  - Hydrolases [D08.811.277]
    - Peptide Hydrolases [D08.811.277.656]
      - Serine Proteases [D08.811.277.656.959]
        
        Serine Endopeptidases [D08.811.277.656.959.350]
        
        Acrosin [D08.811.277.656.959.350.030]
        
        Cathepsin G [D08.811.277.656.959.350.066]
        
        Chymases [D08.811.277.656.959.350.103]
        
        Chymotrypsin [D08.811.277.656.959.350.176]
        
        Complement Factor B [D08.811.277.656.959.350.198]
        
        Complement Factor D [D08.811.277.656.959.350.200]
        
        Complement Factor I [D08.811.277.656.959.350.210]
        
        Endopeptidase K [D08.811.277.656.959.350.247]
        
        Enteropeptidase [D08.811.277.656.959.350.284]
        
        Factor VIIa [D08.811.277.656.959.350.300]
        
        Factor IXa [D08.811.277.656.959.350.310]
        
        Factor Xa [D08.811.277.656.959.350.315]
        
        Factor XIa [D08.811.277.656.959.350.320]
        
        Factor XIIa [D08.811.277.656.959.350.324]
        
        Fibrinolysin [D08.811.277.656.959.350.330]
        
        Furin [D08.811.277.656.959.350.353]
        
        Granzymes [D08.811.277.656.959.350.397]
        
        High-Temperature Requirement A Serine Peptidase 1 [D08.811.277.656.959.350.420]
        
        High-Temperature Requirement A Serine Peptidase 2 [D08.811.277.656.959.350.431]
        
        Kallikreins [D08.811.277.656.959.350.442]
        
        Lactoferrin [D08.811.277.656.959.350.471]
        
        Mannose-Binding Protein-Associated Serine Proteases [D08.811.277.656.959.350.501]
        
        Myeloblastin [D08.811.277.656.959.350.530]
        
        Pancreatic Elastase [D08.811.277.656.959.350.560]
        
        Plasminogen Activators [D08.811.277.656.959.350.635]
        
        Pronase [D08.811.277.656.959.350.638]
        
        Proprotein Convertase 1 [D08.811.277.656.959.350.640]
        
        Proprotein Convertase 2 [D08.811.277.656.959.350.646]
        
        Proprotein Convertase 5 [D08.811.277.656.959.350.648]
        
        Proprotein Convertase 9 [D08.811.277.656.959.350.718]
        
        Reelin Protein [D08.811.277.656.959.350.753]
        
        Subtilisins [D08.811.277.656.959.350.787]
        
        Thrombin [D08.811.277.656.959.350.855]
        
        Tissue Plasminogen Activator [D08.811.277.656.959.350.875]
        
        Trypsin [D08.811.277.656.959.350.895]
        
        Tryptases [D08.811.277.656.959.350.902]
        
        Urokinase-Type Plasminogen Activator [D08.811.277.656.959.350.910]
        
        Venombin A [D08.811.277.656.959.350.955]

Fibrinolysin Preferred

Concept UI: M0008432
Registry Number: EC 3.4.21.7
Scope Note: A product of the lysis of plasminogen (profibrinolysin) by PLASMINOGEN activators. It is composed of two polypeptide chains, light (B) and heavy (A), with a molecular weight of 75,000. It is the major proteolytic enzyme involved in blood clot retraction or the lysis of fibrin and quickly inactivated by antiplasmins.
Terms: Fibrinolysin Preferred Term
Term UI T016303
Date04/01/1992
LexicalTag NON
ThesaurusID NLM (1993); Plasmin
Term UI T016305
Date01/01/1999
LexicalTag NON
ThesaurusID BAN (19XX); Protease F
Term UI T016306
Date03/05/1984
LexicalTag NON
ThesaurusID UNK (19XX); Glu-Plasmin
Term UI T016304
Date10/10/1984
LexicalTag NON
ThesaurusID UNK (19XX)

Fibrogammin Narrower

Thrombolysin Narrower

Fibrinolysin MeSH Descriptor Data 2024