MeSH Browser

MeSH Heading: Cyclin-Dependent Kinase Inhibitor p21
Tree Number(s): D12.644.360.225.500; D12.776.157.687.250; D12.776.167.187.500; D12.776.476.225.500; D12.776.624.776.355.500; D12.776.660.720.250
Unique ID: D050759
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050759
Scope Note: A cyclin-dependent kinase inhibitor that mediates TUMOR SUPPRESSOR PROTEIN P53-dependent CELL CYCLE arrest. p21 interacts with a range of CYCLIN-DEPENDENT KINASES and associates with PROLIFERATING CELL NUCLEAR ANTIGEN and CASPASE 3.
Entry Term(s): CDK2-Associated Protein 20 kDa; CDKN1 Protein; CDKN1A Protein; Cdk-Interacting Protein 1; Cdk2 Inhibitor Protein; Cell Cycle Regulator p21; Cyclin Kinase Inhibitor p21; Cyclin-Dependent Kinase Inhibitor 1A Protein; Senescent Cell-Derived Inhibitor Protein 1; p21 Cell Cycle Regulator; p21 Cyclin Kinase Inhibitor
Pharm Action: Protein Kinase Inhibitors
Public MeSH Note: 2006; CYCLIN-DEPENDENT KINASE INHIBITOR P21 was indexed under CYCLINS 1993-2005, & under CELL CYCLE PROTEINS 2005
History Note: 2006(1993)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2017/05/24

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adverse effects (AE)

agonists (AG)

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biosynthesis (BI)

blood (BL)

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chemistry (CH)

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deficiency (DF)

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economics (EC)

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immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Cyclin-Dependent Kinase Inhibitor p21 MeSH Descriptor Data 2024