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Interleukin-1 Receptor-Associated Kinases MeSH Descriptor Data 2022


MeSH Heading
Interleukin-1 Receptor-Associated Kinases
Tree Number(s)
D08.811.913.696.620.682.700.526
D12.776.476.563.526
Unique ID
D053592
RDF Unique Identifier
http://id.nlm.nih.gov/mesh/D053592
Scope Note
A family of intracellular signaling kinases that were identified by their ability to signal from the activated INTERLEUKIN-1 RECEPTORS. Signaling from these kinases involves their interaction with SIGNAL TRANSDUCING ADAPTOR PROTEINS such as MYELOID DIFFERENTIATION FACTOR 88 and TNF RECEPTOR-ASSOCIATED FACTOR 6.
Entry Term(s)
IL-1 Receptor-Associated Kinase
IRAK Kinases
IRAK-1 Kinase
IRAK-2 Kinase
IRAK-3 Kinase
IRAK-4 Kinase
Interleukin-1 Receptor-Associated Kinase
Interleukin-1 Receptor-Associated Kinase 1
Interleukin-1 Receptor-Associated Kinase 2
Interleukin-1 Receptor-Associated Kinase 3
Interleukin-1 Receptor-Associated Kinase 4
Registry Number
EC 2.7.11.1
Related Numbers
EC 2.7.11.1
Public MeSH Note
2007; INTERLEUKIN-1 RECEPTOR-ASSCIATED KINASES was indexed under PROTEIN-SERINE-THREONINE KINASES & INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS 2006, & under PROTEIN KINASES 1996-2006
History Note
2007(1996)
Date Established
2007/01/01
Date of Entry
2006/07/05
Revision Date
2021/05/21
Interleukin-1 Receptor-Associated Kinases Preferred
Interleukin-1 Receptor-Associated Kinase 4 Narrower
Interleukin-1 Receptor-Associated Kinase 3 Narrower
Interleukin-1 Receptor-Associated Kinase 1 Narrower
Interleukin-1 Receptor-Associated Kinase 2 Narrower
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