MeSH Browser

MeSH Heading: Paxillin
Tree Number(s): D12.644.360.024.316; D12.776.157.057.092; D12.776.476.024.397; D12.776.512.374; D12.776.744.665
Unique ID: D051419
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D051419
Scope Note: Paxillin is a signal transducing adaptor protein that localizes to FOCAL ADHESIONS via its four LIM domains. It undergoes PHOSPHORYLATION in response to integrin-mediated CELL ADHESION, and interacts with a variety of proteins including VINCULIN; FOCAL ADHESION KINASE; PROTO-ONCOGENE PROTEIN PP60(C-SRC); and PROTO-ONCOGENE PROTEIN C-CRK.
Public MeSH Note: 2006; PAXILLIN was indexed under CYTOSKELETAL PROTEINS & PHOSPHOPROTEINS 1991-2005
History Note: 2006(1991)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2016/03/30

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Paxillin MeSH Descriptor Data 2024