MeSH Browser

MeSH Heading: X-ray Repair Cross Complementing Protein 1
Tree Number(s): D12.776.157.687.813; D12.776.260.963; D12.776.660.720.813
Unique ID: D000076105
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D000076105
Scope Note: A poly(ADP)-ribose-binding protein that functions in the rejoining of DNA single-strand breaks that arise following treatment with alkylating agents or ionizing radiation. It interacts with DNA LIGASE III and POLY ADP RIBOSE POLYMERASE in BASE EXCISION REPAIR, and may also function in DNA processing and chromosome recombination in GERM CELLS.
Entry Term(s): XRCC1 DNA Repair Protein; XRCC1 Protein
Public MeSH Note: 2018; X-RAY REPAIR CROSS COMPLEMENTING PROTEIN 1 was indexed under DNA-BINDING PROTEINS 1994-2017
History Note: 2018 (1994)
Date Established: 2018/01/01
Date of Entry: 2017/07/11
Revision Date: 2017/06/29

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

X-ray Repair Cross Complementing Protein 1 MeSH Descriptor Data 2024