MeSH Browser

MeSH Heading: Transcription Factor AP-2
Tree Number(s): D12.776.260.760; D12.776.930.907
Unique ID: D050656
RDF Unique Identifier: http://id.nlm.nih.gov/mesh/D050656
Annotation: see SCR for organism-specific terms
Scope Note: A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.
Entry Term(s): AP-2 Enhancer Binding Protein; AP-2 alpha Protein; AP-2 beta Protein; AP-2 epsilon Protein; AP-2 gamma Protein; AP-2delta Protein; Activator Protein AP-2; Enhancer-Binding Protein AP-2; TFAP2B Protein; TFAP2alpha Protein; Transcription Factor AP-2 alpha Protein; Transcription Factor AP-2 beta Protein; Transcription Factor AP-2 delta Protein; Transcription Factor AP-2 epsilon Protein; Transcription Factor AP-2 gamma Protein; Transcription Factor AP-2alpha; Transcription Factor AP-2beta; Transcription Factor AP-2epsilon; Transcription Factor AP-2gamma; Transcription Factor AP2; Transcription Factor Ap-2delta
Previous Indexing: DNA-Binding Proteins (1987-2005); Transcription Factors (1987-2005)
Public MeSH Note: 2006; TRANSCRIPTION FACTOR AP-2 was indexed under TRANSCRIPTION FACTORS & DNA-BINDING PROTEINS 1987-2005
History Note: 2006(1987)
Date Established: 2006/01/01
Date of Entry: 2005/06/30
Revision Date: 2013/07/09

Allowable Qualifiers: administration & dosage (AD)

adverse effects (AE)

agonists (AG)

analysis (AN)

antagonists & inhibitors (AI)

biosynthesis (BI)

blood (BL)

cerebrospinal fluid (CF)

chemical synthesis (CS)

chemistry (CH)

classification (CL)

deficiency (DF)

drug effects (DE)

economics (EC)

genetics (GE)

history (HI)

immunology (IM)

isolation & purification (IP)

metabolism (ME)

pharmacokinetics (PK)

pharmacology (PD)

physiology (PH)

poisoning (PO)

radiation effects (RE)

standards (ST)

supply & distribution (SD)

therapeutic use (TU)

toxicity (TO)

ultrastructure (UL)

urine (UR)

Concept UI: M0151839
Scope Note: A family of DNA binding proteins that regulate expression of a variety of GENES during CELL DIFFERENTIATION and APOPTOSIS. Family members contain a highly conserved carboxy-terminal basic HELIX-TURN-HELIX MOTIF involved in dimerization and sequence-specific DNA binding.
Terms: Transcription Factor AP-2 Preferred Term
Term UI T181842
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Activator Protein AP-2
Term UI T181838
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); AP-2 Enhancer Binding Protein
Term UI T627038
Date01/06/2005
LexicalTag NON
ThesaurusID NLM (2006); Enhancer-Binding Protein AP-2
Term UI T181844
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006); Transcription Factor AP2
Term UI T181843
Date01/01/1955
LexicalTag NON
ThesaurusID NLM (2006)

Concept UI: M0151827
Terms: Transcription Factor AP-2 beta Protein Preferred Term
Term UI T621909
Date12/06/2004
LexicalTag NON
ThesaurusID NLM (2006); AP-2 beta Protein
Term UI T622148
Date12/06/2004
LexicalTag NON
ThesaurusID NLM (2006); TFAP2B Protein
Term UI T586326
Date05/11/2004
LexicalTag ABX
ThesaurusID NLM (2006); Transcription Factor AP-2beta
Term UI T577040
Date03/15/2004
LexicalTag NON
ThesaurusID NLM (2006)

Concept UI: M0396304
Terms: Transcription Factor AP-2 alpha Protein Preferred Term
Term UI T621908
Date12/06/2004
LexicalTag NON
ThesaurusID NLM (2006); TFAP2alpha Protein
Term UI T575117
Date03/02/2004
LexicalTag NON
ThesaurusID NLM (2006); Transcription Factor AP-2alpha
Term UI T458475
Date08/22/2001
LexicalTag NON
ThesaurusID NLM (2006); AP-2 alpha Protein
Term UI T575115
Date03/02/2004
LexicalTag NON
ThesaurusID NLM (2006)

Transcription Factor AP-2 MeSH Descriptor Data 2024